Having WBC levels higher than the normal range is referred to as leucocytosis. Leucocytosis can be caused by smoking or by severe trauma causing tissue damage.
The spleen is an organ that regulates the levels of WBCs in your body. Individuals who have had to get a splenectomy (surgical removal of the spleen) either due to a ruptured spleen or for disease related reasons, will have a drastic increase in WBCs.
Taking a lot of medication can cause your body to experience leucocytosis. Medication that has shown to cause leucocytosis are anti-asthma drugs such as salbutamol, as well as corticosteroids, epinephrine, heparin, lithium, and chemotherapy drugs like the granulocyte colony-stimulating factor (G-CSF).
Elevated levels of the different types of WBCs can indicate a specific condition.
- Elevated neutrophil levels can indicate a bacterial infection or a high level of psychological stress.
- High lymphocyte levels can indicate a viral infection, whooping cough, or mononucleosis.
- An increase in monocytes can indicate a fungal infection, malaria, or tuberculosis.
- High levels of eosinophils can indicate an allergic reaction, autoimmune diseases, or parasitic worms.
- High basophil levels can indicate cancer, chickenpox, or hypothyroidism.
Generally speaking, infections, inflammatory diseases such allergies, inflammatory bowel syndrome, or rheumatoid arthritis as well leukaemia or Hodgkin’s lymphoma can raise your overall WBC levels significantly.
Pregnant women usually have high levels of white blood cells that can reach 13,000 WBCs per microliter and sometimes more. These high levels of WBCs are not only due to the pregnancy itself but also to the physical and mental stress associated with it.
Symptoms of leucocytosis can be frequent fever, bleeding or bruising, fatigue, dizziness, excessive sweating, vision problems, lack of appetite, weight loss, breathing problems and pain in arms and legs.
It is important to know that if your leucocytosis is caused by mental health issues or by a medication, you may not have any symptoms. [9,10]